1.23 Bottari., Ann.
An indirect evidence in favour of 1,3-hydride shift of the Schiff base 5, isolated from o -phenylenediamine and salicylaldehyde ( 6 showed reluctance to undergo cyclization at room temperature.
R 19, 225 (1988).
Rf:.06 (10 methanol in chloroform).The term alkoxy may included lower alkoxy and higher alkoxy.Hetero-Michael Conjugate Additions -Amino idee de cadeaux mariage ester and its derivatives are attractive targets for chemical synthesis of products with a wide range of biological activities and pharmacological properties.32) NMR (CDCl3,.32 (3H, t, J8.28 (3H,.36 (3H,.68-3.77 (2H, br.28 (2H, q, J8.60 (2H,.43 (2H, d, J8.50 (1H,.63 (1H, d, J8.86 (1H, d, J8.22.The heterocyclic moiety in the terms a heterocycliccarbonyl heterocyclicoxycarbonylamino and heterocyclicsulfonyl may be one mentioned above as a heterocyclic group.Alumina doped with KF can ionize C-acids up to pKa.Halo-substitutions, either on the aryl amine or the arylboronic acid, remained unaffected under the reaction conditions.Process 23 The object compound (I-9) or its salt can be prepared by subjecting a compound (I-8) or its salt to reduction.
47) (E)-Methyl 7-(2-aminophenyl)-6-heptenoate NMR (CDCl3,.52 (2H,.70 (2H,.26 (2H, dt,.5,.5.37 (2H, t,.5.68 (3H,.72 (2H,.04 (1H, dt, J15,.5.91 (1H, d, J15.67 (1H, d, J7.73.
Chem., 44, 1268 (1989).
10) NMR (CDCl3,.37 (3H,.46 (3H,.95-7.00 (3H,.14-7.55 (11H,.84 (1H, d, J8.31 (1H, d, J3.38 (1H, d,.5 Hz).
Barbosa-J Barron-D Beltran-JL Sanznebot-V Pkpot, a Program for the Potentiometric Study of Ionic Equilibria in Aqueous and Nonaqueous Media analytica chimica acta 1995, Vol 317, Iss 1-3, pp 75-81 4/96.
The reaction temperature of this reaction is not critical and the reaction is usually carried out under cooling to heating.
Multipurpose kinagdc(MW) non-linear regression program chemometr intell LAB 39: (1) 77- 14/97.
Magnesium, calcium, etc., the hydroxide or carbonate or bicarbonate thereof, trialkylamine.g.Neher-Neumann E Liquid junction potential in potentiometric titrations.Process 19 The object compound (I-2) or its salt can be prepared by reacting a compound (I-1) or its salt with substituted or unsubstituted N-containing heterocyclic compound or lower alkylhydrazine.NMR (CDCl3,.26 (3H, t,.5.93 (2H,.35 (3H,.39 (2H,.31 (3H,.77-3.97 (2H,.16 (2H, q,.5.84 (1H, dt, J15, 1.73-6.82 (2H,.88-7.01 (4H,.10-7.21 (4H,.29 (2H,.This reaction is usually carried out in a conventional solvent which does not adversely influence the reaction such as diethyl ether, tetrahydrofuran, dioxane, N,N-dimethylformamide or the like.34) mass (m/z 734 (M1).21) NMR (CDCl3,.32 (3H,.39 (3H,.43 (4H, t, J6.36 (3H,.56 (4H, t, J6.26 (2H,.32 (1H, br t,.5.90-6.98 (3H,.10-7.32 (9H,.38-7.55 (3H,.82 (1H, d,.5 Hz).Magnesium, calcium, etc., the hydride or hydroxide or carbonate or bicarbonate thereof.Or the like, in which preferable one is phthaloyl or tert-butoxycarbonyl.Process 21 The object compound (I-5) or its salt can be prepared by reacting a compound (I-4) or its salt with N-containing heterocyclic compound or lower alkylamino(lower)alkylamine.1) NMR (dmso-d6,.14 (2H, t, J6.53 (2H, t, J6.28-7.48 (4H,.10 (2H, d, J8.20 (2H, d, J8.30 (2H, d, J8.36 (2H, d, J8 Hz).